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北五加皮又名香加皮,习惯上被作为“祛风湿、强筋骨”药来应用。不少地方南、北五加皮不分,处方上开五加皮,常给北五加皮。北五加皮制作五加皮酒,已有发生中毒的报道。并且指出含有强心甙,但未引起足够的重视,至今北五加皮仍被作为五加皮来使用。我们临床上曾遇到因处方上开五加皮而取药时给北五加皮引起北五加皮中毒病例2例:1例为住院风心病人,心衰住院后用毛地黄毒甙治疗,配合服中药,处方中有“五加皮”,实际给的是北五加皮。每剂12克,服用三剂后出现心率减慢和多源性多发性室性期前收缩,呈三联
North Wujiapi, also known as Xiangjiapi, has traditionally been used as a “rheumatism, strong bones and muscles” medicine. In many places, there is no distinction between North and South, and five prescriptions are added to the skin, often to North plus Peel. North Wujiapi made Wujiapi wine, and there have been reports of poisoning. It also pointed out that it contains strong heart palpitations, but it did not attract enough attention. To date, P. jasminoides has been used as Wujiapi. We have encountered clinically two cases of bevacizumab poisoning caused by adding P. acuminata to the prescription when taking Acanthopanax on the prescription: 1 patient is a hospitalized patient with rheumatic heart disease and treated with digoxigenin after hospitalization for heart failure. In combination with traditional Chinese medicines, there are “Five plus skins” in the prescription, but the actual amount is Beiwujiapi. Each dose of 12 grams, after taking three doses, the heart rate slows down and multi-source multiple ventricular premature contraction occurs.