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目前研究发现,高载量HBV-DNA水平和慢性乙型肝炎(CHB)并发症发生增高有关,而处于免疫耐受期的CHB患者,其病情进展过程不明。我们对57例HBV-DNA高且处于免疫耐受期的慢乙肝患者病情进展进行了研究。先对每例患者进行首次肝活检。随访5年后,对仍处于免疫耐受期的患者,再次行肝活?
The current study found that high-load HBV-DNA levels and chronic hepatitis B (CHB) complications related to increased, while in immune tolerance of CHB patients, the progression of the disease is unknown. We studied the progression of 57 chronic hepatitis B patients with high HBV-DNA and immunocompromised disease. The first liver biopsy was performed on each patient. After 5 years of follow-up, patients who are still in immunocompromised stage will be treated again for liver function.