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目的研究诱发因素对未足月胎膜早破患者的影响及相关性。方法收集未足月胎膜早破患者的临床资料,并进行回顾性分析,与文献结合进行分析,确定感染、人工流产史、瘢痕子宫为未足月胎膜早破的诱发因素,根据是否合并明显诱发因素分为两组,观察组(60例,伴明显诱发因素),对照组(50例,不明原因),比较两组患者的临床资料、分娩及新生儿情况。结果观察组年龄、感染率、瘢痕子宫、人工流产史较对照组高,孕周较对照组低;组间差异有统计学意义(P<0.05)。观察组正常胎位(20.00%)低于对照组(60.00%),新生儿1 min Apgar评分、发生体重低于对照组,窒息率(21.67%)高于对照组(4.00%),组间比较,P<0.05。研究组胎儿宫内窘迫、5 min Apgar评分、畸形、死亡率等与对照组比较无统计学差异(P>0.05)。结论 1产妇年龄、人工流产史、生殖道感染与妊娠结局相关;2伴随明显诱因的未足月胎膜早破患者,母婴不良结局发生率高;3临床应根据诱发因素的不同采取针对性处理措施,以便降低母婴死亡率,保证良性妊娠结局。
Objective To study the influence of the predisposing factors on the patients with preterm premature rupture of membranes. Methods The clinical data of patients with preterm premature rupture of membranes were collected and analyzed retrospectively. Combined with the analysis of the literature, the authors identified the history of infection and induced abortion, and the factors contributing to the premature rupture of membranes in scarring uterus. Obvious evoked factors were divided into two groups, the observation group (60 patients with significant predisposing factors), the control group (50 patients, unknown reasons), the clinical data of two groups were compared, childbirth and neonatal conditions. Results The age, infection rate, scar uterus and abortion history of the observation group were higher than those of the control group and gestational age was lower than that of the control group. The difference between the two groups was statistically significant (P <0.05). In the observation group, the normal fetal position (20.00%) was lower than that of the control group (60.00%), the Apgar score of the newborn was 1 min, the body weight was lower than that of the control group, and the asphyxia rate was 21.67% higher than that of the control group (4.00% P <0.05. There was no significant difference in the fetal distress, 5-minute Apgar score, deformity and mortality in the study group compared with the control group (P> 0.05). Conclusion 1 maternal age, history of abortion, reproductive tract infection and pregnancy outcome; 2 with a clear incentive for premature rupture of membranes in patients with maternal and child adverse outcomes; 3 clinical should be based on the different factors to be taken Measures to reduce maternal and infant mortality and ensure benign pregnancy outcomes.