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目的分析中国(未包括香港、澳门特别行政区和台湾地区,下同)2006年流行性脑脊髓膜炎(流脑)重点监测省及国家级监测点流行病学监测和实验室监测结果,评价流脑监测现状,为预防控制流脑爆发、流行及探索经济有效的预防控制策略提供依据。方法利用重点监测省及监测点上报的资料、中国疾病预防控制中心(CDC)传染病预防控制所国家流脑实验室检测资料及法定传染病报告系统的资料,对2006年监测结果进行分析。结果全国2006年流脑报告发病率<0.2/10万,重点监测省中以安徽省发病数较多(261例);监测重点省<15岁儿童平均发病率为0.45/10万,儿童、学生报告病例数分别占重点监测省报告病例总数的25.35%和41.31%。重点监测省报告病例中检出A群脑膜炎奈瑟菌(Neisseria meningitidis,Nm)占44.83%,C群Nm占41.38%;健康人群中检出A群Nm占17.76%,B群Nm占48.68%,C群Nm占17.11%;健康人群A群Nm抗体阳性率平均为78.36%,C群为58.67%。结论流脑流行菌群仍以A群Nm为主,C群Nm检出增多;健康人群带菌以B群Nm为主,C群Nm抗体阳性率明显低于A群。应针对薄弱环节,继续加强流脑监测,防止流脑爆发、流行。
Objective To analyze epidemiological surveillance and laboratory monitoring results of epidemic cerebrospinal meningitis (meningitis) in China (excluding Hong Kong, Macao Special Administrative Region and Taiwan, the same below) in 2006 and national monitoring points, The status of brain monitoring provides a basis for prevention and control of the outbreak of epidemic encephalitis, epidemic and exploration of cost-effective prevention and control strategies. Methods The monitoring results of 2006 were analyzed based on the information reported by key monitoring provinces and monitoring points, the detection data of the national meningitis laboratory of the CDC CDC and the reporting system of notifiable infectious diseases. Results The incidence of meningitis in the whole country in 2006 was <0.2 / 100 000, and the number of illnesses in Anhui Province was mainly monitored in the key counties (261 cases). The average incidence of children <15 years old in monitoring key provinces was 0.45 / The number of reported cases accounted for 25.35% and 41.31% of the total number of reported cases in key monitoring province. Neisseria meningitidis group A (Nm) accounted for 44.83% and C group Nm accounted for 41.38% in the reported cases of key monitoring provinces. Among the healthy population, Nm accounted for 17.76% of A group and N of B group accounted for 48.68% , C group Nm accounted for 17.11%; healthy group A group Nm antibody positive rate was 78.36%, C group was 58.67%. Conclusion The prevalence of meningococcal neoplasia is still mainly A group Nm, while that of C group Nm is higher than that of A group. The positive rate of Nm antibody of group C is lower than that of A group. Should focus on the weak links, continue to strengthen the meningococcal monitoring to prevent the outbreak of epidemic encephalitis, epidemics.