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目的和方法 :促肾上腺皮质激素释放激素 (ｃｏｒｔｉｃｏｔｒｏｐｉｎｒｅｌｅａｓｉｎｇｈｏｒｍｏｎｅ ,ＣＲＨ)是一种重要的中枢发热介质。为进一步观察ＣＲＨ在大鼠ＬＰＳ性发热中的作用 ,本研究观察了第三脑室注射ＣＲＨ受体拮抗剂α-ｈｅｌｉｃａｌＣＲＨ( 9- 41 )对ＳＤ
Aims and Methods: Corticotropin releasing hormone (CRH) is an important central heating medium. In order to further observe the role of CRH in the development of LPS-induced fever in rats, we observed the effects of CRH receptor antagonist α-helical CRH (9-41)