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目的分析天津市2 01 2年1~1 1月份疑似预防接种异常反应的发生特征,评价预防接种异常反应监测系统的运转情况、疫苗接种安全性。方法通过A E F I信息管理系统收集天津市2 0 1 2年1~1 1月份疑似预防接种异常反应个案数据,采用描述性方法进行流行病学分析。结果全市2012年报告A E F l个案1 136例,其中一般反应948例;异常反应159例;心因性反应1例;偶合症25例;待定3例。病例发生在1d及以内最为多见,构成比为81%,其他依次随时间推移而逐步减少。流脑疫苗反应增长率与所有接种反应增长值基本一致。天津市1 136例中及时报告的有1 129例,48h内及时报告率99.38%。各区县均达到国家及天津市标准。结论通过监测数据表明,天津市的A E F I监测系统运转正常;目前所使用的疫苗安全性和预防接种服务质量良好;A E F I主要发生在低年龄儿童、NIP疫苗、首剂接种和接种早期;应加强自费疫苗的使用情况监测和人员培训,定期开展A E F I工作督导,确保监测工作质量。
OBJECTIVE: To analyze the occurrence characteristics of suspected immunization anomalous response from January to January in 2001 in Tianjin City, evaluate the operation status of vaccination abnormal reaction monitoring system and the safety of vaccination. Methods Data of suspected cases of abnormal immunization from January to January in 2011 in Tianjin were collected through the A E F I information management system and the descriptive method was used for epidemiological analysis. Results A total of 136 cases were reported in the whole city in 2012, including 948 cases of general reaction, 159 cases of abnormal reaction, 1 case of cardiogenic reaction, 25 cases of coupling syndrome and 3 cases of pending treatment. Case occurred in 1d and less than the most common, the composition ratio of 81%, followed by others gradually decreased over time. The growth rate of meningococcal vaccine response was basically consistent with the growth of all vaccination responses. There were 1,129 timely reports in 1,136 cases in Tianjin and 99.38% in 48 hours. All districts and counties have reached the national and Tianjin standards. Conclusions The monitoring data show that the AEFI monitoring system in Tianjin is operating normally; the vaccine safety and vaccination services currently in use are of good quality; AEFI occurs mainly in children with low age, NIP vaccine, inoculation and early vaccination of the first dose; Vaccine use monitoring and staff training, regular AEFI work supervision, to ensure the quality of monitoring work.