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目的 观察利维爱及补肾中药对绝经后骨质疏松症的防治作用。方法 对 35例绝经妇女每日顿服利维爱 1 2 5mg ,34例绝经妇女口服强骨胶囊 1粒 /次 ,3次 /d。观察其治疗前后临床症状 ,骨密度及代谢生化指标及副作用。结果 服药前后两组临床症状均明显改善 ,骨密度有所上升。利维爱组尿Ca/Cr、尿HOP/Cr、血Ca水平明显改善 ,补肾中药组骨代谢生化指标改善不明显 ,但利维爱组副作用较补肾中药组大。结论 直接应用性激素治疗组在防治绝经后骨质疏松方面效果更显著 ,补肾中药组在改善症状及维持骨量方面疗效显著且副作用小 ,对用性激素替代治疗有禁忌或顾虑及不能耐受其副作用的患者 ,是一种有效的治疗途径。
Objective To observe the prevention and treatment of postmenopausal osteoporosis by Levi and kidney invigorating herbs. Methods Thirty-five menopausal women were served with 125 mg daily, and 34 cases of menopausal women were orally administered with Qiangu capsule 1 capsule 3 times daily. Before and after treatment to observe the clinical symptoms, bone mineral density and biochemical indicators and side effects. Results The clinical symptoms of both groups were significantly improved before and after taking the medicine, and the BMD increased. Urinary Ca / Cr, urinary HOP / Cr, blood Ca levels were significantly improved in Levi group, and the biochemical parameters of bone metabolism in Bushen Chinese medicine group were not significantly improved. However, the side effects in Levi group were larger than that in Bushen Chinese medicine group. Conclusion The direct application of hormone therapy group is more effective in preventing and treating postmenopausal osteoporosis. The traditional Chinese medicine of tonifying kidney group has significant curative effect and little side effect in improving the symptoms and maintaining the bone mass. It has taboo or concerns for sex hormone replacement therapy and can not tolerate its side effects Of patients, is an effective treatment.