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目的:观察可变流量鼻塞持续气道正压通气(N-CPAP)治疗新生儿呼吸衰竭的疗效。方法:对2007年12月～2008年12月在青海省红十字医院NICU住院的18例不同原因引起的的新生儿呼吸衰竭患儿使用N-CPAP仪进行治疗,观察治疗前后临床症状,血气指标和胸片改善情况。结果:治愈14例,可变流量N-CPAP治疗成功率77.78%,其余4例中的2例因无效改为机械通气(其原因可能与上机时间较晚有关),另外2例早产儿合并先天性心脏病,治疗第2天家属放弃治疗而死亡,病程中未发现气胸、出血、感染等并发症。结论:使用可变流量N-CPAP治疗新生儿呼吸衰竭治疗效果显著,具有无创、简便、并发症少、疗效高的特点,值得推广使用。
Objective: To observe the effect of variable flow nasal continuous positive airway pressure (N-CPAP) on neonatal respiratory failure. Methods: From December 2007 to December 2008, 18 children with neonatal respiratory failure caused by different causes in the NICU of Qinghai Provincial Red Cross Hospital were treated with N-CPAP instrument. The clinical symptoms, blood gas indexes And chest X-ray to improve the situation. Results: 14 cases were cured, the success rate of variable flow N-CPAP treatment was 77.78%, and 2 cases of the other 4 cases were changed to mechanical ventilation because of the invalidation (the reason may be related to the late operation), and the other 2 cases were merged Congenital heart disease, the treatment of family members to give up treatment on the 2nd day of death, no pneumothorax, bleeding, infection and other complications were found. CONCLUSION: The treatment of neonatal respiratory failure with variable flow N-CPAP is effective and has the characteristics of noninvasiveness, simplicity, less complications and high curative effect, which is worth popularizing.