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目的:探讨阿昔洛韦联合地塞米松治疗单纯疱疹病毒性脑炎的临床效果。方法:选取本院2010年7月-2013年7月本院接受的80例单纯疱疹病毒性脑炎患者作为研究对象,采用抽签法随机抽取40例患者进行常规治疗,设为对照组;另外40例进行阿昔洛韦联合地塞米松静脉注射治疗,设为观察组。观察两组患者的体温、意识、惊厥、肢体张力等临床特征以及患者的治疗效果。结果:观察组患者进行阿昔洛韦联合地塞米松治疗后体温、意识、惊厥、肢体张力的恢复情况都明显高于对照组患者,差异具有统计学意义(P<0.05);观察组患者的治疗有效率为95.0%明显高于对照组的77.5%,两组相比差异具有统计学意义(x~2=5.681,P<0.05)。结论:对于单纯疱疹病毒性脑炎患者,采用阿昔洛韦联合地塞米松治疗可以提高患者的治疗效果,促进患者的康复。
Objective: To investigate the clinical efficacy of acyclovir combined with dexamethasone in the treatment of herpes simplex virus encephalitis. Methods: 80 cases of herpes simplex virus encephalitis admitted to our hospital from July 2010 to July 2013 were selected as the research object. Forty patients were randomly selected by lottery method for routine treatment as the control group. Another 40 Cases of acyclovir intravenous dexamethasone treatment, as the observation group. Two groups of patients were observed clinical features such as body temperature, consciousness, convulsions, limb tension and the therapeutic effect of the patients. Results: The recovery of body temperature, consciousness, convulsion and limb tension in patients in observation group after treatment with acyclovir and dexamethasone were significantly higher than those in control group (P <0.05). The patients in observation group The effective rate of treatment was 95.0%, which was significantly higher than that of the control group (77.5%). The difference between the two groups was statistically significant (x ~ 2 = 5.681, P <0.05). Conclusion: For patients with herpes simplex virus encephalitis, the combination of acyclovir and dexamethasone can improve the therapeutic effect and promote the recovery of patients.