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目的观察鸦胆子油乳剂联合化疗药物经胸腔置管注入治疗恶性胸腔积液的有效率和安全性。方法对46例恶性胸腔积液患者将中心静脉导管置入胸腔,引流完胸腔积液后将鸦胆子油乳剂联合化疗药物注入胸腔内,观察疗效和副反应。结果CR14例PR23例,总有效率80.4%,未见明显不良反应。结论鸦胆子油乳剂联合化疗药物经胸腔置管注入治疗恶性胸腔积液为一有效方法,可以提高患者生活质量。
Objective To observe the efficiency and safety of Brucea javanica oil emulsion combined with chemotherapeutic drugs in the treatment of malignant pleural effusion by thoracic catheterization. Methods 46 cases of malignant pleural effusion in patients with central venous catheter into the chest, after drainage of pleural effusion after Brucea oil emulsion combined with chemotherapy drugs into the chest cavity, efficacy and side effects were observed. Results CR14 cases PR23 cases, the total effective rate was 80.4%, no obvious adverse reactions. Conclusion Brucea javanica oil emulsion combined with chemotherapy drugs through the thoracic tube into the treatment of malignant pleural effusion is an effective method to improve the quality of life of patients.