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葡萄膜恶性黑色素瘤(uveal melanoma,UM)是成人最常见的眼内原发性恶性肿瘤,在其发生发展过程中可释放多种肿瘤标志物(tumor marker,TM)。寻求有价值的特异性TM对UM早期诊断、靶向治疗和判断预后具有重要意义。我们对UM蛋白标志物及其近年来研究进展作一综述。
Uveal melanoma (UM) is the most common intraocular malignancy of the eye in adults and releases a variety of tumor markers (TM) during its development. The search for valuable and specific TM is of great importance for the early diagnosis, targeted therapy and prognosis of UM. We reviewed the UM protein markers and their progress in recent years.