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目的 研究人工培养蛹虫草 (Cordycepsmilitaris)干燥子实体的化学成分。 方法 利用各种色谱技术进行分离纯化 ,通过理化方法及光谱 (UV ,IR ,HRMS ,EIMS ,1HNMR ,13 CNMR ,FGCOSY ,DEPT ,FGHMQC和FGHMBC)分析鉴定其化学结构。结果 从人工培养蛹虫草干燥子实体的乙醇提取物中分离得到 7个化合物 ,分别鉴定为 :3′ 脱氧腺苷 (3 deoxyadenosine ,1) ,腺苷 (adenosine,2 ) ,N6 甲基腺苷 (N6 methyladenosine,3) ,O5′ 乙酰基虫草素 (O5′ Acetylcordycepin ,4) ,N6 [β (乙酰胺甲酰 )氧乙基 ]腺苷 (N6 [β (acetylcarbamoyloxy)ethyl]adenosine,5 ) ,虫草环肽A(cordycepeptideA ,6 )和麦角甾醇过氧化物 (ergosterolperoxide ,7)。 结论 化合物 (5 )和 (6 )为两个新化合物 ,并首次归属这些化合物波谱信号
Objective To study the chemical composition of artificial fruiting bodies of Cordyceps militaris. Methods A variety of chromatographic techniques were used to separate and purify. The chemical structures were identified by physicochemical methods and spectroscopy (UV, IR, HRMS, EIMS, 1HNMR, 13CNMR, FGCOSY, DEPT, FGHMQC and FGHMBC). Results Seven compounds were isolated from ethanol extracts of artificially cultivated dried fruit bodies of Cordyceps militaris. They were identified as 3′ deoxyadenosine (1), adenosine (2), and N6 methyl adenosine ( N6 methyladenosine, 3), O5′ acetyl cordycepin (O5′ Acetylcordycepin, 4), N6 [β (acetamideamoyloxy)ethyl]adenosine, 5 ), Cordyceps Cytopeptide A (6) and ergosterol peroxide (7). Conclusions Compounds (5) and (6) are two new compounds and belong to the spectrum signal of these compounds for the first time.