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提到药物的不良反应,人们很自然地会想到胃损害、肝损害和肾损害,而对于肺损害却知之甚少。据统计,药物性肺损害占全身药物不良反应的5%~8%,有的可造成肺组织永久性损害,严重者会危及生命。药物性肺疾病由呼吸科或放射科医生首先发现,其他各科均有发生药物性肺疾病的可能。20世纪60年代以后,药物更新换代加速,而医生对新药的认识和临床应用经验不足,药物的不良反应逐渐增多,药物性肺疾病诊断比较困难,很容易造成漏诊或误诊。本专辑介绍日本对于药物性肺损害最新的一些研究资料,供我国医务人员参考学习。本专辑选译自《日本匾師仝雑誌》2006年第134卷第11号“薬剤性肺障害をめぐって”专辑。由大连医科大学附属第一医院万献尧教授审校。
Mentioning the adverse effects of drugs, people naturally think of stomach damage, liver damage, and kidney damage, while little is known about lung damage. According to statistics, drug-induced lung damage accounts for 5% to 8% of systemic adverse drug reactions, and some can cause permanent lung damage, and in severe cases, life-threatening. First of all, drug-induced pulmonary diseases are found by respiratory or radiologists, and other medical subjects are at risk of developing drug-induced lung disease. Since the 1960s, drug replacement has been accelerating. However, doctors’ lack of knowledge on new drugs and clinical application experience has led to the gradual increase of adverse drug reactions. Diagnosis of drug-induced pulmonary diseases is more difficult and can easily result in missed diagnosis or misdiagnosis. This album introduces some of the latest research data on drug-induced lung damage in Japan for reference by medical staff in our country. This album is selected from the “Japanese plaque with the same blog” in 2006 No. 134, No. 11, “薬 剤 sexual disability を め め っ て” album. From Dalian Medical University Affiliated First Hospital Professor Wan Xiangyao proofreading.