有关下丘脑—垂体。肾上腺轴(HPAA)调节中胆碱能神经的作用已见报道。虽然其作用在不同种属动物间存在着差异,但至少是在大鼠,胆碱能神经对HPAA有兴奋作用。关于人类HPAA调节中,胆碱能神经的作用知之甚少。本文作者对正常男性志愿者,用胰岛素引起低血糖,然后给予阿托品阻断胆碱能神经,研究是否可影响促肾上腺皮质激素(ACTH)和β-内啡肽以及可的松的释放。 About the hypothalamus - pituitary. The role of the adrenal axis (HPAA) in regulating cholinergic nerves has been reported. Although its role in different species of animals there are differences, but at least in rats, cholinergic nerve HPAA excited. Little is known about the role of cholinergic nerves in regulating human HPAA. The authors of this study randomized normal male volunteers to insulin-induced hypoglycaemia and then to atropine to block cholinergic nerves. We investigated whether they could affect the release of ACTH and beta-endorphin, and cortisone.