目的:观察限制性输液对老年结直肠癌术后转归的影响。方法:将老年结直肠癌97例,随机分为限制性输液组49例和非限制性输液组48例。限制性输液组术后3天平均每天输液量≤33 ml/(kg.d),非限制性输液组>34 ml/(kg.d),比较两组术前及术后1周血红蛋白、谷丙转氨酶、谷草转氨酶、清蛋白、球蛋白、葡萄糖、尿素、肌酐、钙及镁等水平变化,以及术后首次排气、首次排便、首次进食、首次下床活动、住院时间和不良反应发生情况。结果:限制性输液组术后第1～6天每天平均输液量显著少于非限制性输液组(P<0.05),术后第7天两组每天平均输液量差异不显著(P>0.05);术后首次排气、首次排便、首次进食和首次下床活动时间均显著早于非限制性输液组(P<0.05);术后住院时间两组比较,差异不显著(P>0.05);术后不良反应总发生率显著低于非限制输液组(P<0.05);两组术后生化及血常规检查结果与术前比较,差异均不显著(P>0.05)。结论:术后限制性输液可加速患者康复,降低术后不良反应发生率。 Objective: To observe the effect of restrictive infusion on the prognosis of elderly patients with colorectal cancer. Methods: A total of 97 elderly patients with colorectal cancer were randomly divided into a controlled infusion group (n = 49) and a non-restricted infusion group (n = 48). In the limited infusion group, the average daily infusion volume was less than or equal to 33 ml / (kg.d) for 3 days after operation and> 34 ml / (kg.d) for non-limiting infusion group. The hemoglobin, Alanine aminotransferase, aspartate aminotransferase, albumin, globulin, glucose, urea, creatinine, calcium and magnesium levels, as well as the first postoperative exhaust, first defecation, first feeding, first bed activity, length of stay and adverse reactions . Results: The average daily transfusion volume was significantly less in the restricted transfusion group than in the non-transfusion group (P <0.05), and the average daily transfusion volume was not significantly different between the two groups on the 7th day after operation (P> 0.05) (P> 0.05). The time of the first extubation, the first defecation, the first feeding and the first ambulation time were significantly earlier than those in the non-restrictive infusion group (P <0.05). There was no significant difference in postoperative hospital stay between the two groups (P> 0.05) The total incidence of postoperative adverse reactions was significantly lower than that of the untreated infusion group (P <0.05). The postoperative biochemical and blood test results were not significantly different between the two groups (P> 0.05). Conclusion: Postoperative restrictive infusion can accelerate the recovery of patients and reduce the incidence of postoperative adverse reactions.