大多数急性哮喘发作患者,经支气管扩张药和皮质激素治疗可取得满意效果,而合并呼吸性和(或)代谢性酸中毒病人则易进一步恶化,可能需要插管和机械通气。本试验中选择10例哮喘持续状态患者(男4,女6例),平均年龄45岁,所有病人均有呼吸性酸中毒,或代谢性酸中毒合并呼吸性酸中毒。入院后虽用间羟异丙肾上腺素(Metaproterenol)气雾剂吸入、强的松龙(125mg)和氨茶碱(250mg)静脉给药,其中3例病人还加用肾上腺素皮下注射,但病情均无明显改善。随后通过呼吸面罩吸入氦-氧(He- Most patients with acute asthma have satisfactory results with bronchodilators and corticosteroids, and those with respiratory and / or metabolic acidosis are further exacerbated and may require intubation and mechanical ventilation. In this study, 10 patients with persistent asthma (4 males and 6 females) were selected, with a mean age of 45 years. All patients had respiratory acidosis or metabolic acidosis with respiratory acidosis. Although admitted to the hospital with meta-isoproterenol (Aeromeraproterenol) aerosol inhalation, prednisolone (125mg) and aminophylline (250mg) intravenous administration, of which 3 patients were also treated with subcutaneous injection of epinephrine, but the condition No significant improvement. The respiratory mask is then used to inhale He-