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目的：探讨应用小剂量多巴酚丁胺负荷试验与核素心室造影相结合的方法评估存活心肌的意义。方法：采用静态核素心室造影及小剂量多巴酚丁胺测定３５例陈旧性心肌梗死患者的左心室射血分数、右心室射血分数及局部心室壁运动的变化。结果：静态核素心室造影示平均左心室射血分数为４９．９±１６．５％，右心室射血分数为５１．０±７．２％，心室壁运动异常节段８７个（４１．４％）。给予多巴酚丁胺后平均左心室射血分数为５７．９±１９．２％（Ｐ＜０．０１），右心室射血分数为６１．９±６．１％（Ｐ＜０．０５），静态核素心室造影时８７个心室壁运动异常节段中有４８个（５５．２％）节段心室壁运动恢复正常或改善。结论：多巴酚丁胺核素心室造影是可供临床检测存活心肌安全、可靠的无创性方法。
Objective: To explore the significance of using the combination of low-dose dobutamine stress test and radionuclide ventriculography to evaluate the survival of myocardium. Methods: The changes of left ventricular ejection fraction, right ventricular ejection fraction and local ventricular wall motion in 35 patients with old myocardial infarction were measured by static radionuclide venography and low dose dobutamine. Results: The results of static radionuclide venography showed that the average left ventricular ejection fraction was 49.9 ± 16.5%, right ventricular ejection fraction was 51.0 ± 7.2%, and abnormal ventricular wall motion was 87 (41. 4%). The average left ventricular ejection fraction after dobutamine administration was 57.9 ± 19.2% (P <0.01), and right ventricular ejection fraction was 61.9 ± 6.1% (P <0.05 ), And 48 (55.2%) segments of 87 ventricular wall motion abnormalities recovered normal or improved during static radionuclide ventriculography. Conclusions: Dobutamine nucleus ventriculography is a safe and reliable noninvasive method for the clinical detection of viable myocardium.