目的　探索外科治疗晚期肺癌的新途径 ,将体外循环技术用于晚期已浸润到胸主动脉的肺癌手术治疗 ,使常规方法不能切除的肺癌获得根治性切除。方法　取左侧第 5肋床切口进胸 ,经左肺动脉、降主动脉插管建立体外循环。结果　经心包内切除左全肺 ,切除并置换受肿瘤侵犯的降主动脉 ,患者顺利恢复 ,未见与体外循环相关的并发症。结论　体外循环是侵犯心脏大血管肿瘤外科治疗的有效辅助手段之一。侵犯心脏大血管的肿瘤 ,只要没有广泛的远处转移等手术禁忌证 ,就应该努力应用体外循环技术彻底地予以切除。彻底地切除侵犯心脏大血管的肺癌 ,为晚期肺癌长期生存提供机会 Objective To explore a new way of surgical treatment of advanced lung cancer and to apply the extracorporeal circulation technique in the surgical treatment of advanced lung cancer infiltrated into the thoracic aorta in the late stage and to obtain a radical resection of lung cancer that can not be removed by conventional methods. Methods The left fifth rib bed incision into the chest, the left pulmonary artery, descending aorta catheter to establish cardiopulmonary bypass. The results of percutaneous transarterial resection of the left lung, resection and replacement by the tumor of the descending aorta, the patient recovered successfully, and no complications associated with cardiopulmonary bypass. Conclusion Extracorporeal circulation is one of the effective adjuncts to the surgical treatment of cardiac large vessel tumors. Invasion of the heart of large blood vessels of the tumor, as long as there is no widespread surgical contraindications such as distant metastasis, it should be hard to apply the cardiopulmonary bypass technique to be completely removed. Thoroughly resection of lung cancer that invading the heart and large blood vessels provides an opportunity for the long-term survival of advanced lung cancer