论文部分内容阅读
目的探讨慢性心力衰竭(chronic heart failure,CHF)患者血清心肌肌钙蛋白Ⅰ(cardiac troponinI,cTnI)与室性心律失常的关系。方法根据入院时血清cTnⅠ检测结果将218例CHF患者分为cTnⅠ阳性组(cTnⅠ≥0.05 ng/mL)108例和cTnⅠ阴性组(cTnⅠ<0.05 ng/mL)110例。2组患者均行24 h动态心电图监测。结果cTnⅠ阳性组平均每小时单个室性异位搏动的个数、平均每小时成对室性异位搏动的个数、24 h室性心动过速的次数均明显高于cTnI阴性组(P均<0.05)。多变量logistic回归分析结果显示,cTnⅠ阳性是CHF患者室性心律失常的预测因子。结论cTnⅠ阳性与CHF患者室性心律失常密切相关。
Objective To investigate the relationship between serum cardiac troponin Ⅰ (cTnI) and ventricular arrhythmia in patients with chronic heart failure (CHF). Methods One hundred and eighty-eight patients with cTnⅠ positive (cTnⅠ≥0.05 ng / mL) and cTnⅠ negative (cTnⅠ <0.05 ng / mL) were divided into two groups according to the results of serum cTnⅠin admission. Patients in both groups underwent 24-hour Holter monitoring. Results The average number of single ventricular ectopic beats per hour, the average number of pairs of ventricular ectopic beats per hour and the number of 24-h ventricular tachycardia in cTn Ⅰ -positive group were significantly higher than those in cTnI-negative group (P <0.05). Multivariate logistic regression analysis showed that cTnI positivity was a predictor of ventricular arrhythmias in CHF patients. Conclusions Positive cTnI is closely related to ventricular arrhythmia in patients with CHF.