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有报道,曾患大肠癌者及其无症状的直系亲属结肠上皮细胞异常增殖,口服碳酸钙3个月能显著抑制结肠上皮增生。本研究进一步证实并补充这些发现,同时评估钙剂开始作用时间,钙盐剂型及影响补钙反应的宿主因素。方法:一组35例认为有患大肠癌危险者,其中26例为大肠癌患者无症状的直系亲属,9例有大肠腺瘤既往史者,平均年龄51.6岁。内镜及便隐血检查阴性,除外十二指肠溃疡、肾结石、肾衰及高钙血症。治疗中不
It has been reported that those with colorectal cancer and their asymptomatic immediate family members of colorectal epithelial cells abnormal proliferation, oral calcium carbonate 3 months can significantly inhibit colonic epithelial hyperplasia. This study further confirms and supplements these findings, as well as assessing the onset of calcium, the dosage form of calcium, and the host factors affecting the calcium response. Methods: A group of 35 patients considered to be at risk of developing colorectal cancer, 26 of whom were asymptomatic immediate relatives of colorectal cancer and 9 had a past history of colorectal adenoma with an average age of 51.6 years. Endoscopy and occult blood test negative, except for duodenal ulcer, kidney stones, renal failure and hypercalcemia. Not in treatment