阻塞性睡眠呼吸暂停低通气综合征与高血压

来源 :医学综述 | 被引量 : 0次 | 上传用户：aierlansi

【摘要】

：

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与高血压密切相关,OSAHS是引起高血压的独立危险因素,但其引起高血压的机制尚未十分清楚.睡眠中长期慢性间断性低氧、高碳酸血症,引起

【作者】

：

王晓源

【机构】

：

广西医科大学附属柳州市人民医院呼吸内科

【出处】

：

医学综述

【发表日期】

：

2004年期

【关键词】

：

阻塞性睡眠呼吸暂停低通气综合征高血压内皮素1 持续呼吸道正压通气

【基金项目】

：

柳州市科技攻关课题

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论文部分内容阅读

阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与高血压密切相关,OSAHS是引起高血压的独立危险因素,但其引起高血压的机制尚未十分清楚.睡眠中长期慢性间断性低氧、高碳酸血症,引起交感活性增加、内皮功能障褥、肾素-血管紧张素-醛固酮系统的激活,以及内皮素1、心钠素分泌的异常增多等都可能是高血压发生的重要因素.OSAHS合并的高血压是一种难治性高血压,单纯的药物治疗很难控制血压平稳,同时应用持续呼吸道正压通气是治疗的最佳方案.

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阻塞性睡眠呼吸暂停低通气综合征与高血压

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