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对乙型肝炎(乙肝)病毒感染孕妇采取合理的围分娩期管理以阻断母婴垂直传播是降低我国慢性乙肝感染率的关键。新生儿出生后及时注射乙肝免疫球蛋白,并按照“0、1、6方案”接种乙肝疫苗,可有效阻断乙肝的围分娩期传播。孕妇在晚孕期进行抗病毒治疗可能通过降低母体病毒水平而减少围分娩期传播风险,但抗病毒药物对胎儿的安全性仍需进一步验证。
It is the key to reduce the rate of chronic hepatitis B infection in China by adopting proper management of perinatal delivery to block the vertical transmission of mother and infant to hepatitis B virus (HBV) infected pregnant women. Newborns timely injection of hepatitis B immune globulin after birth, and in accordance with “0,1,6 program ” Hepatitis B vaccine, can effectively block the spread of hepatitis B perinatal delivery. Antiviral treatment of pregnant women during the first trimester may reduce the risk of metastasis during maternal delivery by reducing the level of maternal virus. However, the safety of antiviral drugs for the fetus needs further verification.