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目的探讨外科手术后的原发性高血压病(EH)患者,鼻饲与口服氨氯地平对血压变异性(BPV)的影响。方法将符合条件的103例原发性高血压患者分为鼻饲氨氯地平组(A组)和口服氨氯地平组(B组)治疗4周,治疗前后分别进行动态血压监测的检查。结果 (1)两组患者治疗后的血压变异性均较治疗前明显降低,差异有统计学意义(P﹤0.01);(2)两组间治疗后的血压变异性比较差异无统计学意义(P﹥0.05)。结论苯磺酸氨氯地平片对外科手术后须鼻饲的EH患者,在稳定降压的同时可显著降低血压变异性。
Objective To investigate the effect of nasal feeding and oral amlodipine on blood pressure variability (BPV) in patients with essential hypertension (EH) after surgery. Methods 103 patients with essential hypertension were divided into nasal feeding amlodipine group (A group) and oral amlodipine group (B group) for 4 weeks. Before and after treatment, ambulatory blood pressure monitoring was performed. Results (1) The blood pressure variability of the two groups after treatment was significantly lower than that before treatment, the difference was statistically significant (P <0.01); (2) There was no significant difference in blood pressure variability between the two groups after treatment P> 0.05). Conclusion Amlodipine besylate tablets can significantly reduce the variability of blood pressure in EH patients who need nasal feeding after surgery.