目的探讨不同出生胎龄的早产儿在纠正月龄24个月以内的体格、运动及智能发育趋势,为早产儿早期干预提供理论依据。方法将不同出生胎龄的早产儿分为两组(≥32周组的中晚期早产儿组及<32周组的早期早产儿组),统一对他们进行定期随访,在特定的纠正月龄(6、12、18、24)进行体格、运动及智能发育评定,并观察他们的运动及智能发育在两岁以内的生长发育趋势。结果 1)体格发育:两组早产儿在纠正6月龄的体重、身长及头围的构成比差异均有统计学意义,体重构成比的差异持续至纠正12月龄;2)运动发育指数(psychomotor developmental index,PDI):两组早产儿的PDI在纠正6、12月龄均明显低于85分,早期早产儿组的差距更大,纠正18月龄后两组早产儿无需纠正均可达85分以上;3)智能发育指数(mental developmental index,MDI):两组早产儿的MDI在纠正6、12、18月龄均明显低于85分,早期早产儿组的差距更大,纠正24月龄时MDI无需矫正两组早产儿均可达85分以上。结论早期早产儿组在1岁以内的体格发育存在追赶不足的问题,体重表现的较明显,建议加强早期早产儿组的早期营养强化;两组早产儿纠正24月龄以内的运动及智能发育水平明显低于同龄儿,而在纠正24月龄时均能赶上同龄儿,两组早产儿的运动及智能发育在纠正24月龄内均呈现追赶发育趋势。 Objective To investigate the physical, motor and intelligence development trend of preterm infants with different birth gestations within 24 months of correction, providing a theoretical basis for early intervention of premature infants. Methods The gestational age of preterm infants were divided into two groups (≥32 weeks in the group of early and late preterm children and <32 weeks of early premature children group), they were regularly followed up in a specific correction of age ( 6, 12, 18, 24) for assessment of physical, motor and intellectual development, and observed the growth and development of their motor and intelligence development within two years of age. Results 1) Physical development: The differences of body weight, body length and head circumference of 6-month-old preterm infants in two groups were statistically significant, and the difference of body weight ratio continued to correct 12-month-old. 2) The index of exercise development psychomotor developmental index (PDI): The PDI of preterm infants in both groups were significantly lower than 85 points at 6 and 12 months of correction, and the difference between premature infants and premature infants was even greater. Correcting 18 days of age, 85 points or more; 3) mental developmental index (MDI): The MDI of preterm infants in both groups were significantly lower than 85 at 6, 12 and 18 months of age, and the difference was even greater in premature infants MDI at month-old no need to correct two groups of preterm children up to 85 points or more. Conclusion Early premature infants have less catch-up in physical development within 1 year of age, with more obvious weight performance. It is suggested that early premature infants should be strengthened early nutritionally. Premature infants in both groups should correct the level of exercise and intelligence development within 24 months of age Significantly lower than the same age children, and correct the 24-month-old can catch up with their peers, the two groups of premature children’s exercise and mental development in the correction of 24-month-old are catching development trends.