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某些血液病可采用脾切除治疗,本文仪就几种常见血液病脾切除治疗的机理、指征、疗效及影响预后因素等有关问题作一综述。一、自家免疫性溶血性贫血(AHA):AHA是由于某些因素使体内红细胞膜抗原性发生改变或体内抗体形成器官发生异常,产生了针对自身红细胞抗原的相应抗体,使红细胞发生凝集和在脾内滞留破坏,临床表现为贫血、黄疸、脾肝肿大等。根据自身免疫抗体的类型,可分为温型抗体型及冷型抗体型,前者为不完全抗体,吸附在红细胞表面的受体上。使红细胞致敏,后者为完全抗体,存在于血清中,AHA主要是指温型抗体型。虽可用
Some blood diseases can be treated by splenectomy. This article reviews the mechanisms, indications, curative effects and prognostic factors of several common hematological diseases in splenectomy. A, autoimmune hemolytic anemia (AHA): AHA is due to certain factors that make the body red blood cell membrane antigenic change or antibody in vivo organ abnormalities, resulting in antibodies against their own red blood cell antigen, agglutination of erythrocytes and in Spleen retention damage, clinical manifestations of anemia, jaundice, splenomegaly and so on. According to the type of autoimmune antibodies, can be divided into warm antibody type and cold antibody type, the former is incomplete antibodies, adsorbed on the surface of red blood cells receptors. Erythrocyte sensitization, the latter is completely antibody, exists in the serum, AHA mainly refers to the warm antibody type. Although available