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目的:分析和讨论鼻咽癌照射特别是颞侧照射产生的听力损伤。方法:1990年1月至1996年8月对65例患者分别在放疗前、后及放疗后2年作听力检测2~3次。结果:放疗后2年及再送放疗前后分别感音听力损伤发病率为31(18/58耳)、50%(15/30耳),P<0.01。面颈大野总听力损伤64.3%(18/28耳)>耳前小野30%(9/30耳)。年龄<49岁者听力损伤3/28耳,与≥49岁15/30耳,P<0.01。结论:经TPS计算当鼻咽DT-70Gy时内耳DT从40Gy~54Gy,可引起放射听力损伤.虽可立即出现但更多的是延迟反应。随照射时间延长,照射野大小、年龄而增加,再程放疗可因放射剂量的累积使听力损伤加重。
Objective: To analyze and discuss the hearing damage caused by nasopharyngeal carcinoma, especially radial irradiation. METHODS: From January 1990 to August 1996, 65 patients were examined for hearing 2 to 3 times before and after radiotherapy and 2 years after radiotherapy. RESULTS: The incidence of sensorineural hearing impairment was 31 (18/58 ears) and 50% (15/30 ears), respectively, at 2 years after radiotherapy and before and after radiotherapy, P<0.01. Neck and neck Ohno total hearing loss 64.3% (18/28 ears)> 30% ear (4/30 ears). The age of <49 years old had hearing impairment 3/28 ears, and ≥49 years old 15/30 ears, P<0.01. Conclusion: TPS can be used to calculate DT from 70Gy to 54Gy when DT-70Gy in nasopharyngeal can cause radiological hearing loss. Although immediate, but more delayed response. With the extension of the irradiation time, the size and age of the radiation field increase, and radiation therapy can increase the hearing loss due to the accumulation of radiation dose.