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晚期冠心病是西方国家最常见的致死性疾病之一,近年来在我国的发病率和死亡率也呈明显上升趋势。目前主要的治疗方法包括内科药物治疗以及外科手术,有其局限性。血管新生的基础研究取得了重大进展,为缺血性心脏病的治疗带来了新的思路。现就治疗性血管新生大背景下,肝细胞生长因子对冠心病的治疗作用机制、研究进展、尚存在的问题作一综述。
Late coronary heart disease is one of the most common fatal diseases in western countries. In recent years, morbidity and mortality in our country have also been on the rise. At present, the main treatment methods include medical treatment of internal medicine and surgery, which have their limitations. Significant progress has been made in the basic research of angiogenesis, which brings new ideas for the treatment of ischemic heart disease. Now on the background of the treatment of angiogenesis, the mechanism of treatment of hepatocyte growth factor on coronary heart disease, research progress, there are still problems to be reviewed.