轻链病(Light chain diseas,LCD)是骨髓瘤免疫分类的一个类型,可称“轻链型骨髓瘸”。近年来,我院发现2例LCD和2例罕见的双轻链病(Double light chain disease,DLCD),兹报道如下。 [例1] 孟××,男性,70岁,已婚,汉族,河北省籍,1982年7月28日入院,住院号178297。今年3月起因反复腹泻及左上肢、双下肢间歇性钝痛及麻木感,血沉45mm/时,尿蛋白(-),本周蛋白(±)。拟“骨髓瘤”转来我院。体检:贫血貌,皮肤粘膜无出血点,浅表淋巴结不大。心肺正常。腹软,肝肋下未及,脾肋下2cm。左上肢肌力减退,握力差;肌无萎缩,未引出病理反射。血红蛋白5.9g,白细胞3,100, Light chain diseas (LCD) is a type of immune classification of myeloma that can be called “light chain bone marrow lame”. In recent years, our hospital found 2 cases of LCD and 2 cases of rare double light chain disease (Double light chain disease, DLCD), are reported below. [Example 1] Meng × ×, male, 70 years old, married, Han nationality, Hebei province, July 28, 1982 admission, hospital number 178297. This year in March due to repeated diarrhea and left upper extremity, both lower extremities intermittent dull pain and numbness, erythrocyte sedimentation rate 45mm /, urinary protein (-), protein (±) this week. To be “myeloma” transferred to our hospital. Physical examination: anemia appearance, skin and mucous membrane without bleeding, superficial lymph nodes is not large. Cardiopulmonary normal. Abdominal soft, liver under the ribs, spleen ribs 2cm. Left upper limb muscle weakness, poor grip; muscle no atrophy, did not lead to pathological reflex. Hemoglobin 5.9g, WBC 3,100,