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目的通过多导睡眠图监测探讨慢性阻塞性肺疾病（COPD）缓解期夜间低氧与肺功能轻重程度，有否合并睡眠呼吸暂停（重叠综合症）及肥胖的关系。方法26例COPD患者多导睡眠图监测7h，记录血氧饱合度（SaO2）低于90％时间；平均SaO2，夜间基础SaO2与最低值的差（△SaO2）；SaO2下降大于4％的总次数。结果COPD缓解期夜间低氧和肺功能轻重程度呈正相关，合并睡眠呼吸暂停者及肥胖者均夜间低氧明显。结论COPD缓解期要针对不同病情给予夜间氧疗等措施。
Objective To investigate the relationship between nocturnal hypoxia and pulmonary function in COPD patients with COPD and with or without sleep apnea syndrome (COPD) and obesity. Methods Twenty-six patients with COPD were monitored by polysomnography for 7h. SaO2 was recorded less than 90% of the time. The mean SaO2, nighttime difference between SaO2 and lowest value (△ SaO2) and the total number of SaO2 decreased more than 4% . Results There was a positive correlation between nocturnal hypoxemia and severity of pulmonary function in COPD patients. Obvious nocturnal hypoxia was found in those with sleep apnea and obesity. Conclusion COPD remission for different conditions to give night oxygen therapy and other measures.