来氟米特(leflunomide)与其他免疫抑制剂相比,具有多环节作用(抑制嘧啶合成、抑制蛋白酪氨酸激酶活性等)的特点,并具有抗病毒作用。它最初用于类风湿性关节炎的治疗,以后也用于治疗其他自身免疫性疾病如系统性红斑狼疮(SLE)等。由于该药独特的免疫抑制作用,其在器官移植中的应 Compared with other immunosuppressive agents, leflunomide has the characteristics of multiple links (such as inhibition of pyrimidine synthesis, inhibition of protein tyrosine kinase activity, etc.) and has antiviral effects. It was originally used for the treatment of rheumatoid arthritis and later for the treatment of other autoimmune diseases such as systemic lupus erythematosus (SLE). Due to the unique immunosuppressive effect of this drug, it should be used in organ transplantation