干线型肝纤维化是曼氏和日本血吸虫病的发病和致死的主要原因。多数学者认为化学治疗,除当时可能出现药物毒性反应外,对病人有利而无害处。死虫虽能引起局部的严重反应,但逐步被吸收后只留下轻微的损伤痕迹,因此认为死虫是引起肝纤维化的主因 Mainline liver fibrosis is the leading cause of morbidity and mortality in Manchurian and Japanese schistosomiasis. Most scholars believe that chemotherapy, in addition to the possible drug toxicity at that time, the patient beneficial and harmless. Although dead insects can cause serious local reactions, but gradually absorbed after leaving only traces of minor injuries, so that dead insects is the main cause of liver fibrosis