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鼻腔接种不仅能诱生全身性应答而且还能诱生粘膜性应答,对预防呼吸道疾病很重要。为提高鼻腔接种疫苗的免疫原性,作者对聚氨基葡糖作为释放系统和免疫增强剂进行
Nasal inoculation not only induces systemic responses but also mucosal responses, which are important for the prevention of respiratory diseases. To improve the immunogenicity of nasal vaccination, the authors performed chitosan as a release system and immune enhancer