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目的了解和掌握山东省晚期丝虫病的发病与流行状况。方法对山东原班氏丝虫病流行区基本消灭前后晚期丝虫病发病及流行病学调查情况进行了对比分析。结果防治前后晚期丝虫病病人的主要临床表现为象皮肿、鞘膜积液和乳糜尿。防治前32．00％的象皮肿和31．00％的鞘膜积液患者在40岁以上，而乳糜尿病人73．00％低于40岁，防治后象皮肿和鞘膜积液患者90．00％以上高于40岁，乳糜尿66．70％超过40岁，且女性高于男性。象皮肿、鞘膜积液和乳糜尿从基本消灭前的1．38％、6．14％和0．21％，基本消灭后分别下降到0．20％、0．34％和0．19％。结论基本消灭丝虫病后，象皮肿和鞘膜积液明显下降，但乳糜尿仍有一些新病例出现，所以乳糜尿的监测和治疗应作为晚期丝虫病防治的主要对策。
Objective To understand and master the incidence and prevalence of late filariasis in Shandong Province. Methods The incidence and epidemiological investigation of late filariasis before and after the original endemic filariasis in Shandong were compared. Results The main clinical manifestations of patients with advanced filariasis before and after treatment were astigmatism, hydrocele and chyluria. Pre-control 32.00% of the elephantiasis and 31.00% of the patients with hydrocele over the age of 40, while the chyluria patients 73.00% less than 40 years of age, after treatment of patients with edema and hydrocele 90.00% above 40 years old, 66.70% chyluria over 40 years old, and women than men. The edema, hydrocele and chyluria decreased from 1.38%, 6.14% and 0.21% before they were basically eliminated to 0.20%, 0.34% and 0.19% respectively %. Conclusion After the eradication of filariasis, the edema and hydrocele significantly decreased, but there are still some new cases of chyluria. Therefore, the monitoring and treatment of chyluria should be taken as the main countermeasure for the prevention and treatment of advanced filariasis.