恶性淋巴瘤是一组原发于淋巴结或其它淋巴组织的恶性肿瘤。其发生率据部份地区统计约为3—4/10万,占全部恶性肿瘤的第八位。本病虽系全身性疾病,但临床初期以无痛,进行性淋巴结肿大为特徵,尤其好发于颌下,颈部淋巴结,因此就诊于口腔科者并不少见。由于临床表现复杂,病理分类又不完全统一,因此很容易误诊。本文收集在初诊时不明确或误而最后经病理复查证实的恶性淋巴瘤16例,根据其临床特点 Malignant lymphomas are a group of malignancies that originate in lymph nodes or other lymphoid tissues. The incidence rate is about 3-4 million per 100,000 in some regions, accounting for the eighth place in all malignant tumors. Although this disease is a systemic disease, it is characterized by painlessness and progressive lymphadenopathy in the early stages of the clinical course. It is especially prone to submandibular and cervical lymph nodes. Therefore, it is not uncommon to see a doctor in the department of stomatology. Because of complex clinical manifestations and incomplete classification of pathological classification, it is easy to misdiagnose. This article collected 16 cases of malignant lymphoma that were not clear or wrong at the time of initial diagnosis and were finally confirmed by pathological examination, according to its clinical features.