妊娠期糖尿病(GDM)发病机制不十分确切,认为妊娠期胎盘分泌的拮抗胰岛素的各种激素增加及其造成的胰岛素敏感性降低是导致妊娠期糖尿病发病的主要原因。近年很多研究表明,遗传因素在妊娠期糖尿病的发生发展中起重要作用,一些基因的多态性可能影响到个体妊娠期糖尿病易感性的差异。就近年来有关妊娠期糖尿病基因多态性方面的研究进行综述。 Gestational diabetes mellitus (GDM) pathogenesis is not very exact, that the secretion of gestational placental antagonism of insulin increased hormones and the resulting decrease in insulin sensitivity is the leading cause of gestational diabetes the main reason. In recent years, many studies have shown that genetic factors play an important role in the occurrence and development of gestational diabetes mellitus, some of the genetic polymorphisms may affect the individual differences in gestational diabetes susceptibility. In recent years, the genetic polymorphism of gestational diabetes mellitus were reviewed.