[目的]探讨股骨转移癌病人外科治疗的疗效和意义。[方法]回顾性分析本院2005年3月~2013年8月手术治疗的股骨转移癌病人39例。女18例;年龄39~83岁,平均63岁。男21例;年龄30~86岁,平均63岁。对其预期生存时间及实际生存时间进行评估与对比。对濒临骨折的病人术前进行Mirels评分。股骨近端转移癌25例,其中2例有双侧股骨近端转移病灶。病灶位于股骨颈8例,粗隆间12例,粗隆下7例。股骨干转移癌12例,其中1例为双侧股骨干病理性骨折。股骨远端转移癌2例。术前术后进行疼痛评分。术后分别于3、6、12个月和最后随访时间采用Enneking评分标准对病人进行术后功能评估。[结果]平均随访时间为14个月(1~63个月),其中28例病人死亡,11例病人目前仍生存。死亡病人中位生存时间为8.5个月(1~63个月)。术前术后疼痛评分差异有统计学意义(P<0.05)。实际生存时间大于预期生存时间且差异有统计学意义(P<0.05)。术后分别于3、6、12个月和末次随访时间的Enneking功能评分为14~26分之间。[结论]根据股骨是否存在病理性骨折、濒临骨折、病灶部位、累及范围选择手术治疗方法。作为综合治疗的手段之一,可有效地缓解疼痛,改善肢体功能,提高生存质量。 [Objective] To investigate the efficacy and significance of surgical treatment of patients with femoral metastases. [Methods] A retrospective analysis of 39 patients with femoral metastases who underwent surgery in our hospital from March 2005 to August 2013 was retrospectively analyzed. 18 females; aged 39 to 83 years old, average 63 years old. 21 males; aged 30 to 86 years old, average 63 years old. The expected survival time and the actual survival time to assess and compare. Patients on the verge of fracture were preoperative Mirels score. There were 25 cases of proximal femur metastasis, of which 2 cases had bilateral proximal femur metastasis. Lesions in the femoral neck in 8 cases, 12 cases of intertrochanteric, tuberosity in 7 cases. Twelve cases of metastatic femoral shaft, including 1 case of bilateral femoral shaft fractures. 2 cases of distal femur metastasis. Preoperative and postoperative pain score. Postoperatively, patients were evaluated for postoperative function using the Enneking score at 3, 6, 12 months and at the last follow-up. [Results] The average follow-up time was 14 months (range, 1 to 63 months), of which 28 patients died and 11 patients were still alive. The median survival time for death was 8.5 months (range, 1 to 63 months). Preoperative and postoperative pain scores were statistically significant (P <0.05). The actual survival time is greater than the expected survival time and the difference was statistically significant (P <0.05). The Enneking score at 3, 6, 12 months and the last follow-up was 14 to 26 points after operation. [Conclusion] According to the presence of pathological fractures of the femur, the brink of the fracture, the lesion site, involving the selection of surgical treatment. As one of the means of comprehensive treatment, it can effectively relieve pain, improve limb function and improve the quality of life.