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为探讨去纤酶治疗急性脑梗塞的疗效,对用去纤酶治疗的66例与用低分子右旋糖酐和维脑路通治疗的69例进行了对照观察,同时观察了用药前后血液流变学指标变化。结果表明,去纤酶组总有效率75.76%,对照组59.42%(P<0.05);显效率分别为43.94%和36.23%(P>0.05)。治疗后两组红细胞比容、血小板、胆固醇、甘油三酯均明显降低,而且去纤酶组纤维蛋白原,高、低切全血粘度、低密度脂蛋白亦明显降低。我们认为去纤酶对急性脑梗塞疗效显著,能改善血液流变学指标。
In order to explore the therapeutic effect of defibrase on acute cerebral infarction, 66 cases treated with defibrase and 69 cases treated with low molecular dextran and Weileutong were observed and observed before and after treatment, hemorheological parameters Variety. The results showed that the total effective rate was 75.76% in the defibrase group and 59.42% in the control group (P <0.05). The effective rates were 43.94% and 36.23% respectively (P> 0.05). After treatment, hematocrit, platelets, cholesterol and triglyceride in the two groups were significantly decreased, and fibrinogen, high and low cut whole blood viscosity and low density lipoprotein in defibrase group were also significantly decreased. We believe that defibrase has a significant effect on acute cerebral infarction and can improve hemorheology.