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目的:探讨生长抑素联合垂体后叶素治疗对肝硬化上消化道出血患者生活质量的影响。方法:2011年1月—2015年5月间,对医院住院治疗80例肝硬化上消化道出血患者,根据随机分组法,将其分为对照组(垂体后叶素)和观察组(生长抑素联合垂体后叶素),每组各40例,比较两组治疗的临床疗效、生活质量评分、治疗期间不良反应。结果:与对照组相比,观察组患者的治疗总有效率、治疗后生活质量各维度得分及总分均明显增高(P<0.05);不良反应发生率显著降低(P<0.05)。结论:生长抑素联合垂体后叶素治疗能够有效控制肝硬化上消化道出血患者的出血症状,提高患者的生活质量。
Objective: To investigate the effect of somatostatin combined with pituitrin on the quality of life of patients with cirrhosis and upper gastrointestinal hemorrhage. Methods: From January 2011 to May 2015, 80 hospitalized patients with cirrhosis and upper gastrointestinal bleeding were randomly divided into control group (vasopressin) and observation group Pituitrin), each group of 40 cases, the clinical efficacy of two groups were compared, quality of life score, adverse reactions during treatment. Results: Compared with the control group, the total effective rate of treatment group, the quality of life after treatment and the scores of all dimensions were significantly higher (P <0.05), and the incidence of adverse reactions was significantly lower (P <0.05). Conclusion: Somatostatin combined with pituitrin treatment can effectively control the hemorrhagic symptoms of patients with cirrhosis and upper gastrointestinal bleeding, and improve the quality of life of patients.