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目的评价空气贮留、肺结核与肺功能指数的相关性。方法通过对53例病理或临床证实的肺结核患者,使用螺旋CT分别进行了不同呼吸时相的连续容积数据模式扫描,对肺结核和空气贮留分别进行评分,全部患者作了肺功能检查。结果肺结核和空气贮留分别在234/318和176/318个肺叶中见到,两者平均积分高度相关(r=0.74,P<0.01)。空气贮留积分与肺功能指数相关性:第1秒最大呼气量占用力肺活量百分比(FEV1/FVC)(r=-0.40,P<0.05)、25%肺活量时最大用力呼气流率(FEF25%)(r=-0.50,P<0.05)相关,第1秒最大呼气量(FEV1)(r=-0.47,P<0.01)、用力肺活量(FVC)(r=-0.45,P<0.01)、50%肺活量时最大呼气流率(FEF50%)(r=-0.76,P<0.01)、残气量(RV)(r=0.78,P<0.01)高度相关。结论在肺结核患者中空气贮留与小气道功能指数具有密切相关性。
Objective To evaluate the correlation between air storage, pulmonary tuberculosis and pulmonary function index. Methods Fifty-three patients with pathologically or clinically confirmed pulmonary tuberculosis were scanned with continuous volumetric data of different respiratory phases by spiral CT respectively, and pulmonary tuberculosis and air storage were scored separately. All patients were examined for pulmonary function. Results Pulmonary tuberculosis and air storage were seen in 234/318 and 176/318 lung lobes, respectively. The mean integral between the two was highly correlated (r = 0.74, P <0.01). The correlation between air storage score and pulmonary function index: The percentage of maximal expiratory volume occupancy of vital capacity (FEV1 / FVC) at 1 second (r = -0.40, P <0.05) and the maximum forced expiratory flow rate at 25% (r = -0.47, P <0.01), forced vital capacity (FVC) (r = -0.45, P <0.01) , Maximum expiratory flow rate (FEF50%) at 50% vital capacity (r = -0.76, P <0.01) and RV (r = 0.78, P <0.01). Conclusions Air storage in tuberculosis patients is closely related to small airway function index.