目的:探讨脑神经型吉兰-巴雷综合征的诊断、鉴别诊断、治疗及预后。方法:回顾分析1例脑神经型吉兰-巴雷综合征的临床资料,结合文献对其诊断、鉴别诊断、治疗及预后进行讨论。结果:本病例符合脑神经型吉兰-巴雷综合征的诊断,应用免疫球蛋白、激素、B族维生素药物治疗后痊愈。结论:对感染后出现急性对称性脑神经麻痹的患者,即使无肢体瘫痪,也应考虑到变异型吉兰-巴雷综合征的可能。 Objective: To investigate the diagnosis, differential diagnosis, treatment and prognosis of Guillain-Barre syndrome with cranial nerve. Methods: A retrospective analysis of one case of cranial nerve Guillain-Barre syndrome clinical data, combined with the literature on its diagnosis, differential diagnosis, treatment and prognosis were discussed. Results: This case is in line with the diagnosis of cranial nerve Guillain-Barre syndrome, which is cured by immunoglobulin, hormone and B vitamins. Conclusions: Patients with acute symptomatic cranial nerve palsy after infection should also consider the possibility of variant Guillain-Barre syndrome even without limb paralysis.