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目的探讨还原型谷胱甘肽在治疗乙型肝炎中的辅助作用。方法将60例慢性乙型肝炎患者随机分为治疗组和对照组各30例。治疗组给予还原型谷胱甘肽(古拉定)与复方甘草酸苷(派甘能)及苦黄联合治疗,对照组给予复方甘草酸苷(派甘能)及苦黄联合治疗。结果治疗组总有效率、临床症状及体征均优于对照组,差异有统计学意义(P<0.05)。结论还原型谷胱甘肽不仅参与细胞抗氧化反应,维持机体氧化平衡,还参与了调节细胞增生和机体免疫的作用,与复方甘草酸苷和苦黄联合治疗乙型肝炎,能取得很好的疗效,值得推广。
Objective To investigate the role of reduced glutathione in the treatment of hepatitis B. Methods Sixty patients with chronic hepatitis B were randomly divided into treatment group and control group, 30 cases each. The treatment group was given the combination of reduced glutathione (Guladine) and compound glycyrrhizin (Pycniferol) and Kuhuang, and the control group was given compound glycyrrhizin (Pegangyun) and Kuhuang combined treatment. Results The total effective rate, clinical symptoms and signs in the treatment group were better than those in the control group, the difference was statistically significant (P <0.05). Conclusions Reduced glutathione (GSH) not only participates in the cellular anti-oxidative response, maintains the body’s oxidative balance, but also participates in the regulation of cell proliferation and immunity. Combined with glycyrrhizin and bitter yellow combined treatment of hepatitis B, Efficacy, it is worth promoting.