灭吐灵系一种非吩噻嗪类止吐剂,它与止吐剂甲哌氯丙嗪相似,能阻断突触后多巴胺受体,两者的锥体外系副作用有:各种急、迟发性肌张力障碍和运动障碍及帕金森氏综合征。急性反应通常为自限性的和短暂的,给予苯托品几乎在数分钟内即可发生效果。现报告一例灭吐灵引起延长性的急性运动障碍。病例:女性,38岁。既往史及家族史无神经系统疾病。发生恶心而接受灭吐灵治疗,10毫克每日 Exotoxin A non-phenothiazine antiemetic, similar to the antiemetic agent prochlorperazine, blocks the postsynaptic dopamine receptors, both of which have extrapyramidal side effects: various acute, Delayed dystonia and dyskinesia and Parkinson’s syndrome. Acute reactions are usually self-limiting and transient, giving the benefit of benzopin to occur in minutes. A case of exenatide-induced acute dyskinesia is now reported. Case: Female, 38 years old. Past history and family history of non-neurological diseases. Occurs nausea and metoclopramide treatment, 10 mg daily