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目的:探讨胃镜下碘染色对早期食管癌及癌前病变的诊断价值。方法:将胃镜下200例有可疑食管病患者随机分染色组和对照组,染色组用复方碘溶液胃镜下碘染色、不染色或淡染色的食管病变进行活检病理诊断。对照组仅凭经验直接行病理活检。结果:染色组不染色或淡染色62例,活检发现食管癌21例,其中早期食管癌4例,鳞状上皮异型增生6例,其中重度异型增生5例;对照组100例活检发现食管癌6例,轻中度异型增生5例。两组食管癌诊断率的差异有统计学意义。结论:胃镜下碘染色能减少食管黏膜活检误差,提高食管癌诊断率,有助于发现早期食管癌及其癌前病变,值得临床研究推广应用。
Objective: To investigate the value of iodine staining under endoscopy in the diagnosis of early esophageal cancer and precancerous lesions. Methods: 200 cases with suspicious esophageal disease were randomly divided into control group and control group. The staining group was diagnosed by biopsy with iodine staining, non - staining or light staining of esophageal lesions by compound iodine solution gastroscopy. Control group by pathology biopsy alone. Results: In the staining group, 62 cases were not stained or lightly stained, 21 cases were found esophageal cancer by biopsy, including 4 cases of early esophageal cancer, 6 cases of squamous dysplasia, 5 cases of severe dysplasia; 100 cases of control group were found esophageal cancer 6 Cases, mild to moderate dysplasia in 5 cases. The difference between the two groups in the diagnosis of esophageal cancer was statistically significant. Conclusion: The iodine staining under endoscopy can reduce the biopsy error of esophageal mucosa, improve the diagnostic rate of esophageal cancer, help to find the early esophageal cancer and precancerous lesions, and worthy of clinical application.