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目的评价左炔诺孕酮宫内节育系统(LNG-IUS)治疗子宫腺肌病的临床疗效。方法 30例患子宫腺肌患者,在放置LNG-IUS环前和放置后1,3,6个月,比较放置前后痛经程度、月经量、盆腔痛或性交痛、贫血的变化。结果放置LNG-IUS环1个月后,月经量减少1/2~2/3,盆腔痛或性交痛明显减轻或消失,血红蛋白量上升至正常值。放置LNG-IUS环6个月后,患者痛经症状明显缓解或消失;与治疗前相比差异有统计学意义(P<0.01或P<0.05)。结论LNG-IUS为子宫腺肌病患者提供了非手术治疗的新方法。
Objective To evaluate the clinical efficacy of levonorgestrel intrauterine system (LNG-IUS) in the treatment of adenomyosis. Methods Thirty patients with adenomyosis were treated with LNG-IUS before and 1, 3, and 6 months after placement. The changes of dysmenorrhea, menstrual flow, pelvic or painful intercourse and anemia were compared before and after placement. Results After placing LNG-IUS ring for 1 month, menstrual flow decreased by 1/2 ~ 2/3, pelvic pain or pain of sexual intercourse was significantly reduced or disappeared, hemoglobin increased to normal value. After 6 months, the symptoms of dysmenorrhea were relieved or disappeared in patients with LNG-IUS ring. The difference was statistically significant (P <0.01 or P <0.05) before treatment. Conclusion LNG-IUS provides a new approach to nonsurgical treatment of patients with adenomyosis.