论文部分内容阅读
目的探讨经直肠超声造影(CEUS)下前列腺穿刺活检诊断前列腺特异抗原(PSA)灰区前列腺癌的价值。方法对102例PSA灰区可疑前列腺癌患者行前列腺穿刺活检,其中CEUS组56例,普通直肠超声(TRUS)组穿刺活检46例。结果 CEUS组56例患者共接受穿刺442针,平均7.9针;TURS组46例接受穿刺377针,平均8.2针。CEUS组发现前列腺癌9例,阳性率为16.1%,TURS组6例,阳性率为13.0%,两组阳性率差异无统计学意义(P>0.05)。而穿刺组织病理标本显示,CEUS组阳性针数44针,阳性率为10%;TURS组阳性针数21针,阳性率为5.6%,两者阳性率差异有统计学意义(P<0.05)。两组患者穿刺均无严重并发症发生。结论 CEUS下前列腺穿刺活检安全可靠,可提高PSA灰区前列腺癌的检出率。
Objective To investigate the value of transurethral ultrasound guided prostate biopsy (CEUS) in the diagnosis of prostate-specific antigen (PSA) gray-scale prostate cancer. Methods Totally 102 prostate cancer patients with suspected PSA were enrolled in this study. Among them, 56 patients in the CEUS group and 46 in the transrectal ultrasound group (TRUS) were biopsied. Results In the CEUS group, 56 patients underwent 442 punctures, an average of 7.9 punctures. In the TURS group, 46 patients received 377 punctures, an average of 8.2 needles. In the CEUS group, 9 cases of prostate cancer were found, with a positive rate of 16.1% and 6 cases of TURS. The positive rate was 13.0%. There was no significant difference between the two groups (P> 0.05). The puncture histopathology showed that the number of positive stitches in CEUS group was 44 stitches, the positive rate was 10%. The number of positive stitches in TURS group was 21 stitches, the positive rate was 5.6%. There was significant difference between the two groups (P <0.05). No serious complications occurred in both groups. Conclusions The prostate biopsy under CEUS is safe and reliable, which can improve the detection rate of prostate cancer in the area of PSA gray matter.