一般认为,氟喹诺酮类广谱抗生素不良反应轻微,在美国已成为最常用抗生素。然而,近年来出现的某些严重不良反应事件,使某些氟喹诺酮类被停用或限制使用。如替马沙星可引起溶血、肾功能衰竭及低血糖,格帕沙星及司帕沙星引起QT间期延长,曲伐沙星引起肝毒性等。有限的资料表明,加替 Generally believed that fluoroquinolone broad-spectrum antibiotics minor adverse reactions in the United States has become the most commonly used antibiotics. However, certain serious adverse events that have occurred in recent years have disabled or restricted the use of certain fluoroquinolones. Such as tebufenoxine can cause hemolysis, renal failure and hypoglycemia, grepafloxacin and sparfloxacin caused QT prolongation, trovafloxacin caused liver toxicity. Limited information shows that Gatti