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目的探讨经鼻持续正压通气(nCPAP)对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)合并急性缺血性脑卒中(AIS)患者神经功能恢复的影响。方法按照OSAHS及AIS的诊断标准选取42例OSAHS合并AIS患者(简称OA组),评估患者的神经功能缺损情况。随机分为干预组20例和对照组22例,对照组患者进行急性脑卒中的常规治疗,干预组在常规治疗基础上加用nCPAP治疗。治疗1月后复查多导睡眠图(PSG)并再次评估患者的神经功能缺损程度,观察其变化。结果 OA干预组较对照组患者神经功能缺损程度改善明显(P<0.05),具有统计学意义。结论 nCPAP治疗可改善OSAHS合并AIS患者的呼吸暂停,促进神经功能的恢复。
Objective To investigate the effect of nCPAP on neurological function in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and acute ischemic stroke (AIS). Methods According to the diagnostic criteria of OSAHS and AIS, 42 OSAHS patients with AIS (OA group) were selected to evaluate the neurological deficits in patients. Randomly divided into intervention group of 20 patients and control group of 22 patients, the control group of patients with conventional treatment of acute stroke, the intervention group on the basis of conventional therapy plus nCPAP treatment. After 1 month of treatment, polysomnography (PSG) was reviewed and the degree of neurological deficit was evaluated again to observe the changes. Results Compared with the control group, the degree of neurological deficit in OA intervention group was significantly improved (P <0.05), which was statistically significant. Conclusions nCPAP treatment can improve the apnea of OSAHS patients with AIS and promote the recovery of neurological function.