论文部分内容阅读
目的观察三氧化二砷治疗骨髓增生异常综合征(MDS)的疗效和不良反应。方法 40例MDS患者分为两组,一组应用三氧化二砷,一组给予必要的对症治疗。观察各自的疗效及三氧化二砷的毒副作用。结果 2个疗程后,三氧化二砷治疗组与对照组的总有效率及感染率差异均有统计学意义(P<0.05)。三氧化二砷主要不良反应为肝功能损害、轻度浮肿、手足麻木及便秘。结论三氧化二砷治疗MDS疗效确切且不良反应少,值得临床推广应用。
Objective To observe the efficacy and adverse reactions of arsenic trioxide in the treatment of myelodysplastic syndrome (MDS). Methods 40 cases of MDS patients were divided into two groups, one group of arsenic trioxide, one group give the necessary symptomatic treatment. To observe the respective efficacy and side effects of arsenic trioxide. Results After 2 courses of treatment, the total effective rate and infection rate of the arsenic trioxide treatment group and the control group were significantly different (P <0.05). The main adverse reactions of arsenic trioxide are liver dysfunction, mild edema, numbness of hands and feet and constipation. Conclusion Arsenic trioxide treatment of MDS exact effect and fewer adverse reactions, it is worthy of clinical application.