【摘 要】
：
Objective:To investigate the feasibility of subtraction coronary computed tomographic(CT)angiography(SubCCTA)to decline calcium artifacts and improve diagnostic
【机 构】
：
Department of Radiology,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Te
论文部分内容阅读
Objective:To investigate the feasibility of subtraction coronary computed tomographic(CT)angiography(SubCCTA)to decline calcium artifacts and improve diagnostic accuracy in the presence of coronary calcification and analyze the factors that influence SubCCTA.Methods:A total of 294 patients suspected of having coronary artery diseases underwent coronary computed tomographic angiography(CCTA)and SubCCTA.Coronary stenoses were blindly evaluated by two experienced radiologists,which were compared with invasive coronary angiography(ICA).Multiple statistical indexes were adopted to analyze the value of SubCCTA for the diagnosis of calcium stenoses.Results:The diagnosable rate of SubCCTA was 67.2％(n=197),and the non-diagnosable rate was 32.8％(n=97).Using SubCCTA,the false positive rate decreased from 56.5％ to 17.4％,and the corresponding diagnostic accuracy was increased from 83.6％ to 92.9％.Univariate logistic regression analysis showed that height(OR=1.029,95％CI=1.001-1.058),weight(OR=1.025,95％CI=1.004-1.046),left ventricular size(OR=1.018,95％CI=1.007-1.030),cardiothoracic ratio(OR=39.917,95％CI=1.244-1281.098),the average heart rate(OR=0.866,95％CI=0.836-0.896)and heart rate range(OR=0.882,95％CI=0.853-0.912)might be the factors influencing SubCCTA.Conclusion:This study suggested that SubCCTA could help improve diagnostic accuracy in the presence of calcium plaques.Moreover,several factors were discovered for the first time to possibly influence SubCCTA,which will be helpful in improving the subtracted image quality.
其他文献
Vestibular schwannomas(VS)are benign tumors of the vestibular nerve.The common first symptoms are hearing loss and tinnitus,followed by imbalance,vertigo,and facial nerve involvement.The subjective symptoms of VS patients are not consistent with the sever
目的优化紫姜药材中甲氧基黄酮的提取工艺。方法采用超声提取法,在单因素考察的基础上,结合信息熵-响应面法对乙醇体积分数、超声时间、液料比进行考察,以紫姜中6种主要甲氧基黄酮类成分的含量为评价指标,根据信息熵理论,赋予各指标权重系数,计算综合评分。通过Design-Expert 10.0.7软件分析各因素间的交互作用,得出优化的提取工艺,并对该优化工艺进行验证实验。结果优化的工艺条件为:乙醇体积分数为60%,液料比为12∶1,超声提取2次,每次25 min,甲氧基黄酮类成分的综合评分为1.024,验证实验结果
The use of an antibiotic with immunomodulatory properties could be fascinating in treating multifactorial inflammatory conditions such as ulcerative colitis(UC).We report our investigations into the immunomodulatory properties of levornidazole,the S-enant
Objective:Patients suffered a lot from decompensated vestibular vertigo.Pharmacotherapy and vestibular rehabilitation training have been proven to be effective
Migraine is one of the most common and highest burdens of disease.As a primary cerebral dysfunction illness,migraine might exhibit other system-related symptoms,including vestibular and cochlear symptoms.With the publication of the diagnostic criteria of
目的研究蚊子草正丁醇部位的化学成分。方法利用硅胶柱色谱、凝胶柱色谱、ODS柱色谱及半制备高效液相色谱法对蚊子草的正丁醇部位化学成分进行分离,利用核磁共振波谱对分离得到的化合物进行结构鉴定。结果运用色谱与波谱技术,共分离鉴定了10个化合物,分别是去甲丁香色原酮-7-O-β-D-吡喃葡萄糖苷(1)、萹蓄苷(2)、山柰酚-3-O-α-L-鼠李糖苷(3)、槲皮素(4)、没食子酸(5)、槲皮素3-O-6″-乙酰基-β-D-吡喃半乳糖苷(6)、山柰酚-3-O-β-D-吡喃葡萄糖苷(7)、松脂醇-4-O-吡喃葡萄糖苷(
Objective Mild encephalopathy with reversible splenial lesion(MERS)is associated with a variety of infections and anti-epileptic drug withdrawal.Here we report the clinical characteristics of H1N1 influenza A-associated MERS based on our experience of fou
目的建立能同时测定羽裂蟹甲草花中7-羟基香豆素(HC)、7-羟基-8-甲氧基香豆素(HMC)和7β-D-葡萄糖-8-羟基香豆素(GC)含量的高效液相色谱-二极管阵列检测器(HPLC-PDA)法。方法采用Kromasil C 18色谱柱(250 mm×4.6 mm,5μm),以甲醇-四氢呋喃-10 mL·L-1醋酸(27∶7∶66)为流动相;流速:0.8 mL·min-1;检测波长:325 nm。结果HC、HMC和GC质量浓度分别在1~120、1~120、2~12
目的建立银柴胡药材中甾醇类成分α-菠甾醇和豆甾-7-烯醇的含量测定方法。方法采用高效液相蒸发光散射检测法(HPLC-ELSD),SHIMADZU Shim-pack GIST C 18色谱柱(250 mm×4.6 mm,5μm);流动相为甲醇-水(98∶2);流速:1 mL·min-1;柱温:40℃;检测器漂移管温度:70℃;喷雾器温度:30℃;载气流速:1.6 L·min-1;进样量:50μL。结果在该色谱条件下,α-菠甾醇和豆甾-7-烯醇分离完全,质量浓度分
目的考察安神益智合剂对力竭游泳小鼠的抗疲劳作用及机制。方法采用一次性力竭游泳方式制作运动性小鼠疲劳模型,记录小鼠力竭游泳时间,用分光光度法测定血清尿素氮(BUN)、乳酸(LD)、乳酸脱氢酶(LDH)、肌糖原和肝糖原含量,酶联免疫法测定睾酮和皮质酮含量,RT-PCR和Western Blot法测定肌肉组织中相关基因的转录和翻译水平。结果与正常组比较,模型组小鼠血清睾酮/皮质酮(T/C)比值、肝糖原和肌糖原含量均显著下降,而血清LD、LDH和BUN含量均显著升高。与模型组比较,安神益智合剂给药组小鼠的力竭游泳