作者等以吡喹酮总量60mg/kg二天疗法治疗了慢性血吸虫病合并迁肝13例、慢活肝和肝炎后肝硬化15例,单纯晚期血吸虫病腹水、肝脾肿大及切脾后患者26例。疗程中未见特殊反应和肝功能恶化。出院后随访3～4年,血吸虫病合并慢性肝炎、肝硬化的28例,治后症状均有改善,约1/3劳动力增强,蜘蛛痣多数明显缩小;血清蛋白电泳:治前球蛋白增高的20例,11 The authors used praziquantel 60mg / kg two days therapy for chronic schistosomiasis in 13 cases of liver transplantation, chronic liver and liver cirrhosis in 15 cases, simple advanced schistosomiasis ascites, hepatosplenomegaly and splenectomy patients 26 cases. No special treatment during treatment and deterioration of liver function. After discharge from hospital for 3 to 4 years, schistosomiasis with chronic hepatitis, cirrhosis in 28 cases, post-treatment symptoms were improved, about 1/3 of the workforce increased, the majority of spider nevus significantly reduced; serum protein electrophoresis: elevated pre-treatment globulin 20 cases, 11